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Which of the following provide support for the dopamine hypothesis of schizophrenia?

Evidence for the dopamine hypothesis. Stimulants such as amphetamine, and cocaine increase the levels of dopamine in the brain and can cause symptoms of psychosis, particularly after large doses or prolonged use.

What is the dopamine hypothesis of schizophrenia a level?

The Dopamine Hypothesis was proposed by Arvid Carlsson and suggests that schizophrenia is caused by too much dopamine - or too many dopamine receptors - in key areas of the brain. Dopamine systems in the mesolimbic pathway may contribute to the positive symptoms of schizophrenia (such as hallucinations).

Which dopamine pathway is associated with schizophrenia?

A number of investigators propose that negative and cognitive symptoms of schizophrenia are associated with hypofunction of the mesocortical pathway. This tract is made up of dopaminergic neurons that project from the ventral tegmental area to the prefrontal cortex.

How does dopamine contribute to schizophrenia?

The authors hypothesize that schizophrenia is characterized by abnormally low prefrontal dopamine activity (causing deficit symptoms) leading to excessive dopamine activity in mesolimbic dopamine neurons (causing positive symptoms).