Medication SummaryThe goal of pharmacotherapy is to relieve pain and minimize complications. Currently, no medications are used to treat acute pancreatitis specifically. Therapy is primarily supportive and involves intravenous (IV) fluid hydration, analgesics, antibiotics (in severe pancreatitis), and treatment of metabolic complications (eg, hyperglycemia and hypocalcemia). Show
 Analgesics, OtherClass SummaryPain control is essential for quality patient care. It ensures patient comfort, promotes pulmonary toilet, and has sedating properties, which are beneficial for patients who have sustained trauma or have painful lesions. Propoxyphene products were withdrawn from the US market on November 19, 2010. The withdrawal was based on new data showing QT prolongation at therapeutic doses. For more information, see the FDA MedWatch safety information. Acetaminophen (Tylenol, Feverall, Aspirin Free Anacin)
Acetaminophen is a peripherally acting drug of choice for mild to moderate pain and elevation of body temperature. Tramadol (Ultram, Ryzolt, Rybix)
Tramadol is a centrally acting analgesic for moderately severe pain. It inhibits the ascending pain pathways, altering perception of and response to pain. It also inhibits reuptake of norepinephrine and serotonin. Meperidine (Demerol)
Meperidine is a synthetic opioid narcotic analgesic for the relief of severe pain. It has multiple actions similar to those of morphine. It may produce less constipation, smooth muscle spasm, and depression of cough reflex than similar analgesic doses of morphine. Antibiotics, OtherClass SummaryAntibiotics are used to cover the microorganisms that may grow in biliary pancreatitis and acute necrotizing pancreatitis. The empiric antibiotic regimen is usually based on the premise that enteric anaerobic and aerobic gram-bacilli microorganisms are often the cause of pancreatic infections. Once culture sensitivities are obtained, the antibiotic regimen can be adjusted accordingly. Imipenem and cilastatin (Primaxin)
Imipenem is a thienamycin derivative with greater potency and broader antimicrobial spectrum than other beta-lactam antibiotics. Cilastatin inhibits dehydropeptidase activity and reduces cilastatin metabolism. Imipenem-cilastatin is used for the treatment of multiple-organism infections in which other agents either do not provide wide-spectrum coverage or are contraindicated because of potential toxicity. The 2 agents are generally administered in a 1:1 ratio. Ampicillin
Ampicillin has bactericidal activity against susceptible organisms. It is an alternative to amoxicillin when the patient is unable to take medication orally. Ceftriaxone (Rocephin)
Ceftriaxone is a third-generation cephalosporin with broad-spectrum gram-negative activity; it has lower efficacy against gram-positive organisms and higher efficacy against resistant organisms. Ceftriaxone arrests bacterial growth by binding to 1 or more penicillin-binding proteins.
Author Coauthor(s) Chief Editor Acknowledgements Tushar Patel, MB, ChB Professor of Medicine, Ohio State University Medical Center Tushar Patel, MB, ChB is a member of the following medical societies: American Association for the Study of Liver Diseases and American Gastroenterological Association Disclosure: Nothing to disclose. Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference Disclosure: Medscape Salary Employment Noel Williams, MD Professor Emeritus, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada; Professor, Department of Internal Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada Noel Williams, MD is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada Disclosure: Nothing to disclose. Paul Yakshe, MD Assistant Professor of Medicine, University of Minnesota, Medical Director of Pancreas and Biliary Clinic, Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, Fairview University Medical Center Paul Yakshe, MD is a member of the following medical societies: American College of Gastroenterology, American Pancreatic Association, and American Society for Gastrointestinal Endoscopy Disclosure: Nothing to disclose. What are the main drugs that are used for acute pancreatitis?Omnipen (ampicillin), Primaxin Iv (imipenem/cilastatin), and Rocephin (ceftriaxone sodium) are commonly prescribed for pancreatitis and require a prescription.
What is the treatment for pancreatic necrosis?Surgery remains the gold standard in the treatment of infected pancreatic necrosis, 48 and necrosectomy and continuous closed lavage was successful in 67% of our patients with infected necrosis.
What antibiotics are used for necrotizing pancreatitis?In patients with infected necrosis, administer antibiotics known to penetrate pancreatic necrosis (eg, carbapenems, quinolones, metronidazole), which may delay or avoid intervention, thereby decreasing morbidity and mortality.
What is the best treatment for acute pancreatitis?Treatment for Pancreatitis. a hospital stay to treat dehydration with intravenous (IV) fluids and, if you can swallow them, fluids by mouth.. pain medicine, and antibiotics by mouth or through an IV if you have an infection in your pancreas.. a low-fat diet, or nutrition by feeding tube or IV if you can't eat.. |
Which of the following medications is used to treat acute pancreatitis with necrosis and infection?
zusammenhängende Posts
Urheberrechte © © 2024 membukakan Inc.
