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Which of the following
claims about the TYR, TRP2, and TRP1 mammalian genes is most likely to be accurate?
A
The TYRTYR, TRP2TRP2, and TRP1TRP1 genes are located next to each other on a single chromosome and are organized into an operon.
B
The TYRTYR, TRP2TRP2, and TRP1TRP1 genes may be located on different chromosomes but are activated by the same transcription factor.
C
The TYRTYR, TRP2TRP2, and TRP1TRP1 genes are identical genes since they are activated by the same transcription
factor.
D
The TYRTYR, TRP2TRP2, and TRP1TRP1 genes may be located on different chromosomes but with identical operator sequences.
Which of the following best predicts the phenotype of an individual who is homozygous for this TYR mutation?
A
The mutation will cause a single amino acid change in the TYRTYR protein, which will not be enough to disrupt its function. Therefore, those with this mutation will produce melanin in the hair, skin, and eyes
and tan in response to UVUV radiation.
B
The mutation will cause a single amino acid change in the TYRTYR protein, leading to a nonfunctional TYRTYR protein. Therefore, those with this mutation will lack melanin in the hair, skin, and eyes and will not tan in response to UVUV radiation.
C
The mutation will change all subsequent amino acids in the TYRTYR protein, leading to nonfunctional TYRTYR protein. Since the TRP1TRP1 and TRP2TRP2 genes were not affected, the TRP1TRP1 and TRP2TRP2
proteins will fill the role of the TYRTYR protein. Therefore, those with this mutation will produce melanin in the hair, skin, and eyes in response to UVUV radiation.
D
The mutation will change all subsequent amino acids in the TYRTYR protein, leading to nonfunctional TYRTYR protein. Individuals with this mutation will lack melanin in their hair, skin, and eyes and will not tan in response to UVUV radiation.