Which cell would be more efficient at moving materials in and out of the cell?

==Diffusion and Cell Size== The larger a cell is, the greater the surface area available for diffusion. So why are cells so tiny? Although increasing the size of a cell would increase its surface area, it would also increase the cells volume and thus its demand for nutrients etc. In fact, increasing the size of the cell has a much greater effect on the cells volume than it does on its surface area. If a cell is too large, nutrients simply aren’t able to diffuse through the entire volume of the cell quickly enough. [image:http://i.imgur.com/GEc2npD.png?1] Materials must be able to reach all parts of a cell quickly, and when volume is too large relative to surface area, diffusion cannot occur at sufficiently high rates to ensure this. Smaller cells have a much greater surface area to volume ratio allowing material to diffuse throughout the entire volume of the cell quickly and efficiently. ==Surface Area : Volume== Surface area to volume ratio can also be used to explain the shape of many cells / cellular surfaces. For example the folds inside the mitochondria or the flat pan-cake like structures inside chloroplasts provide a greater surface area on which specific reactions can occur. The folds in the lining of our stomachs or the tiny cellular, finger-like projections that protrude from the wall of the intestine (villi) all act to increase the surface area without increasing the overall size or volume of the organ.

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Learning Objectives
  • Describe the factors limiting cell size and the adaptations cells make to overcome the surface area to volume issue

At 0.1 to 5.0 μm in diameter, prokaryotic cells are significantly smaller than eukaryotic cells, which have diameters ranging from 10 to 100 μm. The small size of prokaryotes allows ions and organic molecules that enter them to quickly diffuse to other parts of the cell. Similarly, any wastes produced within a prokaryotic cell can quickly diffuse out. This is not the case in eukaryotic cells, which have developed different structural adaptations to enhance intracellular transport.

Figure \(\PageIndex{1}\): Relative Size of Atoms to Humans: This figure shows relative sizes on a logarithmic scale (recall that each unit of increase in a logarithmic scale represents a 10-fold increase in the quantity being measured).

In general, small size is necessary for all cells, whether prokaryotic or eukaryotic. Consider the area and volume of a typical cell. Not all cells are spherical in shape, but most tend to approximate a sphere. The formula for the surface area of a sphere is 4πr2, while the formula for its volume is 4πr3/3. As the radius of a cell increases, its surface area increases as the square of its radius, but its volume increases as the cube of its radius (much more rapidly).

Therefore, as a cell increases in size, its surface area-to-volume ratio decreases. This same principle would apply if the cell had the shape of a cube (below). If the cell grows too large, the plasma membrane will not have sufficient surface area to support the rate of diffusion required for the increased volume. In other words, as a cell grows, it becomes less efficient. One way to become more efficient is to divide; another way is to develop organelles that perform specific tasks. These adaptations lead to the development of more sophisticated cells called eukaryotic cells.

Figure \(\PageIndex{1}\): Surface Area to Volume Ratios: Notice that as a cell increases in size, its surface area-to-volume ratio decreases. When there is insufficient surface area to support a cell’s increasing volume, a cell will either divide or die. The cell on the left has a volume of 1 mm3 and a surface area of 6 mm2, with a surface area-to-volume ratio of 6 to 1, whereas the cell on the right has a volume of 8 mm3 and a surface area of 24 mm2, with a surface area-to-volume ratio of 3 to 1.

Smaller single-celled organisms have a high surface area to volume ratio, which allows them to rely on oxygen and material diffusing into the cell (and wastes diffusing out) in order to survive. The higher the surface area to volume ratio they have, the more effective this process can be. Larger animals require specialized organs (lungs, kidneys, intestines, etc.) that effectively increase the surface area available for exchange processes, and a circulatory system to move material and heat energy between the surface and the core of the organism.

Increased volume can lead to biological problems. King Kong, the fictional giant gorilla, would have insufficient lung surface area to meet his oxygen needs, and could not survive. For small organisms with their high surface area to volume ratio, friction and fluid dynamics (wind, water flow) are relatively much more important, and gravity much less important, than for large animals.

However, increased surface area can cause problems as well. More contact with the environment through the surface of a cell or an organ (relative to its volume) increases loss of water and dissolved substances. High surface area to volume ratios also present problems of temperature control in unfavorable environments.

Contributions and Attributions

  • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...ol11448/latest. License: CC BY: Attribution
  • Robert Bear and David Rintoul, Introduction to Cells. October 23, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m47170/latest/. License: CC BY: Attribution
  • eukaryotic. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/eukaryotic. License: CC BY-SA: Attribution-ShareAlike
  • cell. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/cell. License: CC BY-SA: Attribution-ShareAlike
  • prokaryotic. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/prokaryotic. License: CC BY-SA: Attribution-ShareAlike
  • OpenStax College, Introduction. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...e_04_00_00.jpg. License: CC BY: Attribution
  • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...ol11448/latest. License: CC BY: Attribution
  • electron. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/electron. License: CC BY-SA: Attribution-ShareAlike
  • resolution. Provided by: Wiktionary. Located at: en.wiktionary.org/wiki/resolution. License: CC BY-SA: Attribution-ShareAlike
  • OpenStax College, Introduction. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...e_04_00_00.jpg. License: CC BY: Attribution
  • OpenStax College, Studying Cells. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...1_01ab_new.jpg. License: CC BY: Attribution
  • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...ol11448/latest. License: CC BY: Attribution
  • General Biology/Cells/Cell Structure. Provided by: Wikibooks. Located at: en.wikibooks.org/wiki/General...%23Cell_Theory. License: CC BY-SA: Attribution-ShareAlike
  • cell theory. Provided by: Wiktionary. Located at: en.wiktionary.org/wiki/cell_theory. License: CC BY-SA: Attribution-ShareAlike
  • OpenStax College, Introduction. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...e_04_00_00.jpg. License: CC BY: Attribution
  • OpenStax College, Studying Cells. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...1_01ab_new.jpg. License: CC BY: Attribution
  • Diagram of an animal cell in three dimensions. Provided by: Wikimedia. Located at: commons.wikimedia.org/wiki/Fi...dimensions.png. License: Public Domain: No Known Copyright
  • Cell Size. Provided by: OpenStax CNX. Located at: http://cnx.org/contents/[email protected]. License: CC BY-SA: Attribution-ShareAlike
  • Surface Area to Volume Ratios. Provided by: Wikipedia. Located at: en.Wikipedia.org/wiki/Surface-area-to-volume_ratio. License: CC BY-SA: Attribution-ShareAlike
  • Surface area. Provided by: Wiktionary. Located at: en.wiktionary.org/wiki/surface_area. License: CC BY-SA: Attribution-ShareAlike
  • OpenStax College, Introduction. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...e_04_00_00.jpg. License: CC BY: Attribution
  • OpenStax College, Studying Cells. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...1_01ab_new.jpg. License: CC BY: Attribution
  • Diagram of an animal cell in three dimensions. Provided by: Wikimedia. Located at: commons.wikimedia.org/wiki/Fi...dimensions.png. License: Public Domain: No Known Copyright
  • cells.jpg. Provided by: OpenStax CNX. Located at: http://cnx.org/contents/[email protected]. License: CC BY-SA: Attribution-ShareAlike
  • Figure_04_02_02.jpg. Provided by: OpenStax CNX. Located at: http://cnx.org/contents/[email protected]. License: CC BY-SA: Attribution-ShareAlike

Key Points

  • As a cell grows, its volume increases much more rapidly than its surface area. Since the surface of the cell is what allows the entry of oxygen, large cells cannot get as much oxygen as they would need to support themselves.
  • As animals increase in size they require specialized organs that effectively increase the surface area available for exchange processes.

Key Terms

  • surface area: The total area on the surface of an object.


This page titled 4.4: Studying Cells - Cell Size is shared under a CC BY-SA 4.0 license and was authored, remixed, and/or curated by Boundless.

Which cell would be most efficient at moving materials into and out of the cell?

Smaller cells are more efficient at transporting materials in and out and removing waste and also allows more diffusion to happen. When cells remain small, they have a high surface area to volume ratio, which means each cell membrane can efficiently move materials in and out of the cell.

Which cells are more efficient at exchanging materials?

Small cells are more efficient at exchanging materials than large cells because they have more surface area to work with in relation to their size.

Which cell would be most efficient at allowing nutrients and materials diffuse through the cell?

Smaller cells have a much greater surface area to volume ratio allowing material to diffuse throughout the entire volume of the cell quickly and efficiently.

What is the most efficient cell?

Researchers at the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) created a solar cell with a record 39.5% efficiency under 1-sun global illumination. This is the highest efficiency solar cell of any type, measured using standard 1-sun conditions.