What helps prevent molecules from passing through the extracellular space between adjacent cells?

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Which junction prevents molecules from passing through adjacent cells?

1. Occluding junctions seal cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.

What would prevent fluid from leaking between adjacent cells?

Tight junctions form watertight connections between adjacent animal cells. Proteins create tight junction adherence. This tight adherence prevents materials from leaking between the cells; tight junctions are typically found in epithelial tissues that line internal organs and cavities, and comprise most of the skin.