Abstract
Medical science has made tremendous strides in overcoming infectious diseases in the 20th century. Despite this, several epidemics of previously unrecognized diseases have occurred during the last 15 years. These diseases include Lyme disease, Legionnaires' disease, toxic shock syndrome, and AIDS. Examination of past epidemics, including the plague of Athens, the black death, syphilis, and influenza, suggests that the sudden occurrence of diseases that were previously unrecognized is not unusual. Analysis of the new infectious diseases indicates that while all four appeared suddenly, isolated cases of the disease occurred before the actual epidemic. Further, all four new diseases were found to be due to agents or toxins that were not previously recognized. Epidemics due to new infectious diseases may arise by several mechanisms, including mutation of the pathogen to a virulent form and introduction of an infectious agent into a nonimmune population. Environmental and behavioral factors may play an important role, as illustrated by toxic shock syndrome, Legionnaires' disease, and AIDS. On the other hand, epidemic diseases tend to abate over time because of changes in the infecting pathogen and in the host. Hence, epidemics can be seen as cycles; new diseases will arise periodically, occasionally with a devastating outcome. With time the effects of these diseases on the population will ameliorate. The cycle will begin again when a new disease emerges.
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Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. OUP is the world's largest university press with the widest global presence. It currently publishes more than 6,000 new publications a year, has offices in around fifty countries, and employs more than 5,500 people worldwide. It has become familiar to millions through a diverse publishing program that includes scholarly works in all academic disciplines, bibles, music, school and college textbooks, business books, dictionaries and reference books, and academic journals.
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Reviews of Infectious Diseases © 1991 Oxford University Press
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journal article
Infectious Diseases and Human Population HistoryBioScience
Vol. 46, No. 2, Disease Ecology (Feb., 1996)
, pp. 115-126 (12 pages)
Published By: Oxford University Press
//doi.org/10.2307/1312814
//www.jstor.org/stable/1312814
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Journal Information
Published by the American Institute of Biological Sciences (AIBS), BioScience presents readers with timely and authoritative overviews of current research in biology, accompanied by essays and discussion sections on education, public policy, history, and the conceptual underpinnings of the biological sciences. A peer-reviewed, heavily cited, monthly journal with content written and edited for accessibility to researchers, educators, and students alike, BioScience includes articles about research findings and techniques, advances in biology education, professionally written feature articles about the latest frontiers in biology, discussions of professional issues, book reviews, news about AIBS, a policy column (Washington Watch), and an education column (Eye on Education). Roundtables, forums, and viewpoint articles provide the perspectives of opinion leaders and invite further commentary. BioScience is ranked among the top journals in its ISI category (Biology) for both Impact Factor and Citation Half-Life.
Publisher Information
Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. OUP is the world's largest university press with the widest global presence. It currently publishes more than 6,000 new publications a year, has offices in around fifty countries, and employs more than 5,500 people worldwide. It has become familiar to millions through a diverse publishing program that includes scholarly works in all academic disciplines, bibles, music, school and college textbooks, business books, dictionaries and reference books, and academic journals.